Diablo 4 Poison Flurry Rogue Build Guide
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Diablo 4 Poison Flurry Rogue Build Guide

Diablo 4 Poison Flurry Rogue Build Guide: In this Diablo 4 Rogue Class Build, I’ll show you how to play a Poison Flurry Rogue, which is a melee Diablo 4 Build for the Rogue that concentrates on unleashing a flash of attacks to render multiple targets Vulnerable. If you’ve been searching for a good Diablo 4 Poison Flurry Rogue Build that impairs enemies while killing them with Poison, then this guide is for you!

Diablo 4 Poison Flurry Rogue Build Guide

The way this Diablo IV Build works is you’ll engage in fights by charging toward multiple targets with Dash. You’ll then make use of Puncture 3x in order to inflict Slow and Vulnerable, and gain sufficient Energy. This same Skill also lets you accumulate 3 Combo Points to boost Flurry’s overall damage. But before using it, you’ll want to imbue your Dual-Wielded Weapon with Poison so that you can be sure to destroy the majority of your foes. Afterward, it’ll be the perfect time to activate Flurry, which is not only your major source of damage but also a Skill that’ll restore a portion of your HP when you hit Vulnerable enemies. 

Diablo 4 Build for the Poison Flurry Rogue - Condemnation Dual-Wielded Weapon

This standard rotation works well against mobs. You can also start by running toward them and then using Caltrops. Caltrops will make you leap backward to avoid getting attacked while dealing damage and inflicting Slow. And then, you can rush toward your enemies with Dash, followed by Puncture, Poison Imbuement, and Flurry. Alternatively, you can make use of Caltrops near the end of the encounter. If you need to disengage, you can opt for this Skill rather than Dash so enemies won’t be able to reach you. 

When you’re dealing with Elites and Bosses, you’re going to want to make use of Death Trap. This should all pull them within an AoE to deal massive damage even before unleashing Flurry. So you gain a distinct advantage right from the start. It also has a faster cooldown compared to Shadow Clone.

Diablo 4 Poison Flurry Rogue Build Guide – Skill Distribution

Each Diablo 4 Rogue Build is made up of the 6 Active Skills they have equipped and changing these Skills can drastically alter the way the Rogue Class in Diablo IV plays. In this section, we’ll take a look at what Skills you should slot for the Poison Flurry Rogue Diablo 4 Build. Your Skill distribution should look something like this:

Skill Points Spent
 Puncture  1
 Enhanced Puncture  1
 Fundamental Puncture  1
 Flurry  5
 Enhanced Flurry  1
 Improved Flurry  1
 Caltrops  1
 Enhanced Caltrops  1
 Disciplined Caltrops  1
 Dash  1
 Enhanced Dash  1
 Methodical Dash  1
 Exploit  1
 Malice  3
 Poison Imbuement  1
 Enhanced Poison Imbuement  1
 Blended Poison Imbuement  1
 Death Trap  1
 Prime Death Trap  1
 Supreme Death Trap  1

The above list gives you the general order to invest in Skills, but keep in mind that you should prioritize picking up new Active Skills over investing in passives, so pick up passives later if you can get new Active Skills when you level up.

Diablo 4 Rogue Build – How to Handle Packs of Enemies

So there are really several different strategies to employ with this Diablo IV Build for the Poison Flurry Rogue, and these change depending on whether or not you’re facing a large group of enemies or a Boss. Let’s start with a group of enemies first, and we’ll cover how to handle Bosses in the next section.


Dash is one of the Movement Skills of this Poison Flurry Rogue D4 Build that lets you close the gap between you and your enemies. It also allows you to deal moderate damage as you’re surging from one point to the next. The great thing about Dash is its low cooldown so you can certainly use it in dangerous situations when you need enough breathing room to disengage from foes. 

Diablo 4 Rogue Build - Dash Agility Skill

The upgrades that will benefit you greatly are Enhanced Dash together with Methodical Dash. Enhanced Dash buffs the Critical Strike Damage you deal. Comparatively, Methodical Dash reduces Dash’s cooldown even more when used against crowd-controlled targets. You can then activate this in conjunction with Caltrops and Puncture to Slow them down. I’ll discuss these further in the next sections.


The reason why you’ll want 2 Agility Skills for this Diablo IV Build is to have a ton of control and mobility on the battlefield. This is especially important since the Rogue isn’t tanky enough. With Caltrops, you’re able to engage and disengage from fights on top of dealing sufficient damage and inflicting Slow. To enhance this Skill, you’ll need to unlock Enhanced Caltrops and Disciplined Caltrops

Diablo 4 Rogue Build - Caltrops Agility Skill to Slow Down Enemies

Enhanced Caltrops makes it so that enemies receive greater damage from Caltrops while Disciplined Caltrops raises the chances of landing crits, especially when they’re Vulnerable. As such, you can potentially kill them or at the very least, weaken them.


Puncture is a good Basic Skill to have for this Diablo 4 Poison Flurry Rogue Build because you can damage enemies from a shorter distance by throwing blades at them. What’s more, is that since Puncture will be triggered 3x, you’ll always Slow them down. 

Diablo IV Build for the Rogue - Puncture Basic Skill to Throw Blades

Here, you’ll want to take Enhanced Puncture to gain Energy in order to trigger Flurry more often. And then, you’ll be going for Fundamental Puncture to render targets Vulnerable for a couple of seconds. Vulnerable synergizes well with the rest of your Skills so you can deal greater damage.

Poison Imbuement

For the Imbuement Skill, you’re going to pick Poison Imbuement for this D4 Build to deal Poison DoT. This is fairly straightforward as your aim here is to quickly weaken enemies so you can deal killing blows with Flurry.

Diablo IV Build for the Poison Flurry Rogue - Poison Imbuement Skill to Deal Poison Damage

For upgrades, be sure to choose Enhanced Poison Imbuement and Blended Poison Imbuement. With these, you not only raise the duration of Poison but also increase the Poison Damage you deal with Critical Strikes. So you’ll want to search for bonuses to improve your Critical Strike Chance and Critical Strike Damage Bonus.


Right after imbuing your Dual-Wielded Weapons with Poison, you’ll trigger Flurry. This is the Core Skill that will gain more than 100% damage boost provided by Puncture. Flurry essentially allows you to whip up your Weapon to slash enemies in front of you by up to 4x. Aside from investing all 5 points into it, you’ll need to unlock Enhanced Flurry and Improved Flurry

Diablo IV Build for the Poison Flurry Rogue - Flurry Core Skill to Stab and Slash Enemies

Enhanced Flurry is an essential upgrade because as it restores your HP is restored upon attacking Vulnerable targets. Since you’ll weaken them tremendously, the chances of you living longer in combat will be much higher. This also becomes more effective with Improved Flurry, which then turns all nearby enemies Vulnerable, making them susceptible to taking massive damage.

The passives you’ll want to acquire to boost the effectiveness of your Poison Flurry Rogue Diablo 4 Build are Exploit and Malice. Between the two though, you’ll be allocating the most points to Malice to raise your damage against Vulnerable targets.

Diablo IV Build - Malice Passive Skill to Inflict Vulnerable
Diablo IV Build - Exploit Passive Skill

Rogue Build for Boss Fights

Boss fights are handled a bit differently with this Diablo 4 Poison Flurry Rogue Build in terms of the order of Skills you trigger. You can start off with the usual Dash and Caltrops, followed by Death Trap to pull Bosses toward a concentrated AoE. Once entrapped, trigger Puncture 3x to acquire Combo Points and buff Flurry’s damage. And finally, you’ll be activating Flurry. 

Death Trap

Death Trap is a very potent ultimate ability because it deals a whopping 250% damage each against every affected enemy. And it’s made all the more effective thanks to Prime Death Trap and Supreme Death Trap. Prime Death Trap creates a vacuum in the AoE to pull more foes. Meanwhile, Supreme Death Trap rewards you by decreasing the skill’s cooldown from 50 seconds to 40 seconds as long as you slay a target using this ultimate. The more Death Trap kills, the faster you can trigger it again.

Diablo IV Build - Death Trap Ultimate Skill to Trap Enemies and Deal Shadow Damage

Final Tips

For this Diablo 4 Poison Flurry Rogue Build, you should be on the lookout for gear that gives bonuses to Dexterity, Intelligence, Poison Damage, Damage to Close Enemies, Damage to Slowed Enemies, and Core Skill Damage. Of course, Cooldown Reduction and Damage Reduction are good to have as well to be able to activate other Skills more frequently and to survive longer in combat. This is a slow-burn Diablo IV Build of the Rogue Class because it combines the burst damage of Flurry with the DoT of Poison Imbuement.

When it comes to Legendary Aspects, you’ll want to prioritize obtaining the Aspect of Encircling Blades and Aspect of Bursting Venoms. Encircling Blades improves the range of Flurry, allowing you to deal greater damage to nearby enemies, even those positioned at the side or behind you. Meanwhile, Bursting Venoms increases the chances of creating a Poisonous pool. This will deal DoT against enemies standing on top of it as long as you deal Critical Damage using Poison Imbuement. If you’re within the AoE, Poison Imbuement’s cooldown will be zero, allowing you to essentially reactivate the Skill sooner.

Aspect of Encircling Blades

Lastly, you may want to consider picking up Cheat’s Aspect for this Diablo 4 Build. This is defensive in nature such that you end up taking lesser damage against enemies affected by crowd control. So basically, those whom you’re primarily fighting. Additionally, your Movement Speed is boosted when they attack you.

Be sure to check out our Diablo 4 Wiki for any other questions you have about the game and the Builds page if you are looking for more Diablo IV Builds, as well as our Getting Started Guide and Best Class to Play in the Beta Guide if you are looking for more Diablo 4 content!

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